Neurological Abnormalities in Pernicious Anemia Metabolic Mechanisms
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A case of asymptomatic pancytopenia with clinical features of hemolysis as a presentation of pernicious anemia
Pernicious anemia is an autoimmune disease with a variety of clinical presentations. We describe a case of pernicious anemia presenting with pancytopenia with hemolytic features. Further workup revealed very low vitamin B12 levels and elevated methylmalonic acid. It is important for a general internist to identify pernicious anemia as one of the cause of pancytopenia and hemolytic anemia to avo...
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INTRODUCTION Acute portomesenteric vein thrombosis is an uncommon but serious condition with potential sequelae, such as small-bowel gangrene and end-stage hepatic failure. It is known to be caused by various pro-thrombotic states, including hyperhomocysteinemia. We describe what is, to the best of our knowledge, the first reported case of concomitant thrombosis of portal, superior mesenteric a...
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To determine the approximate incidence and clinical features of pernicious anemia in a Korean population, we retrospectively analyzed clinical data for patients with pernicious anemia who were diagnosed between 1995 and 2010 at five hospitals in Chungnam province. Ninety-seven patients were enrolled, who accounted for 24% of patients with vitamin B(12) deficiency anemia. The approximate annual ...
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By KOSMAS A. KIossoGLou, W. J. MITUS AND WILLIAM DAMESHEK B Y NOW, chromosomal aberrations have been well documented in a variety of clinical conditions. Curiously, only scant reports of chromosomal studies in pernicious anemia are available, perhaps because results previously obtained have usually been described as essentially negative. In 1958, Ford et al.1’ reported a case of pernicious anem...
متن کاملPancytopenia in a Patient with Grave's Disease.
Pancytopenia can rarely complicate Grave's disease. It can be due to uncontrolled thyrotoxicosis or as a result of rare side effect of antithyroid medication. Pernicious anemia leading to Vitamin B12 deficiency is another rare associated cause. We report a case of a patient with Grave's disease and undiagnosed pernicious anemia whom was assumed to have antithyroid drug induced pancytopenia. Fai...
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